JAK2/STAT3 Inhibition Attenuates Noise-Induced Hearing Loss
نویسندگان
چکیده
منابع مشابه
JAK2/STAT3 Inhibition Attenuates Noise-Induced Hearing Loss
Signal transducers and activators of transcription 3 (STAT3) is a stress responsive transcription factor that plays a key role in oxidative stress-mediated tissue injury. As reactive oxygen species (ROS) are a known source of damage to tissues of the inner ear following loud sound exposure, we examined the role of the Janus kinase 2 (JAK2)/STAT3 signaling pathway in noise induce hearing loss us...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0108276